Fasting Benefits with Dr. Robin Mesnage

Biohacker's Podcast

24-07-2024 • 48 Min.

In this episode, Teemu Arina and Dr. Robin Mesnage discuss the benefits of therapeutic fasting.

Dr. Robin Mesnage joined Buchinger Wilhelmi at the beginning of 2022 as Lead Data Scientist – after supporting the research team for five years, among others with statistical analyses on the latest studies.

Dr. Mesnage looks back on a long career. His specialist areas are toxicology and chemical regulation, molecular biology and biochemistry, as well as human physiology. In 2008, Dr. Mesnage started his studies in Biology at the University of Caen in Normandy, graduating with a Master’s degree in Cell Biology and a PhD in Molecular and Cell Biology. As a Research Associate at King’s College in London, Dr. Mesnage led a research programme on toxicology in the field of medical genetics and molecular genetics. In 2016, he gained a further Master’s degree in London in Bioinformatics and Systems Biology. In 2018, Dr. Mesnage set up his own company to assess the risk of toxic substances. In addition, he advised health specialists on analysing complex biomedical data.

An experienced researcher, Dr. Mesnage has for the last ten years examined the health effects of pollution caused by pesticides. He has published his findings in over 70 scientific articles that have been cited more than 5,000 times. He has appraised over 100 studies and is editor of three scientific journals.

This conversation was recorded in June 2024.

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Key moments and takeaways:


00:00 Introduction by Teemu Arina

01:24 Shinrin-yoku (forest bathing)

02:09 The life of Otto Buchinger

03:01 About fasting in general

06:04 We are not fasting as we would do in nature

07:05 The cycle of seasons

08:41 Fasting across religions and cultural traditions

11:41 Unclogging your arteries, but also your brain

12:09 The Fasting Box

13:09 How fasting enhances cognitive abilities

14:12 The spiritual aspect

15:01 Ozempic is akin to a religion at this point

16:16 Rapamycin and Spermidine

17:08 Ozempic is easy and addictive

19:09 Educating patients is crucial to long-term success

19:56 What happens during a fast

21:19 Hormonal changes

22:43 Global obesity statistics and projections

24:45 Governments and society address weight loss unsuccessfully

26:15 Foods are made to be addictive

27:35 Drugs will not solve this, only societal change can

29:03 Processed foods high in sugar should have the same warning labels as cigarettes

30:36 The brain rewards energy-dense foods with dopamine

32:07 Stress eating and bears

35:02 Alternating between embolism and catabolism

35:23 Yarrow Willard and the Nature Deficit Disorder

35:58 The Buchinger Wilhelmi clinics and the Fasting Box

37:31 Fasting under expert guidance

38:39 How to adjust to fasting while maintaining a social life

41:25 Two clinics - Marbella (Spain) and Überlingen (Germany)

42:20 Sport, massages, cold exposure and nutrition courses

43:07 Long-term fasting is not the only option available

45:05 Why attempt a longer fast than 48 or 72 hours

46:13 Arrive on a wheelchair, leave walking

46:50 Where to learn more about Buchinger Wilhelmi

47:48 Actual fasting beats any and every shortcut